The supernatural ability to transform into the shape of an animal. It is thought to be passed from victim to victim through various means such as bites, cuts, or curses. Infection rate for those injured is less than 100%.
“Don’t worry. Not everyone injured by a Werewolf inherits the curse.” - Imbri - Festival of Heroes (GS-ADV1)
There is no known cure for lycanthropy.
Some errantly believe the Book of Remedies can offer potion that will work: Hornrash Blossom, Sweet Moss, and Ash of Withered Plum. - The Festival of Heroes (GS-ADV1)
Others believe that a sacrifice to Ninik, god of the hunt, will cure those afflicted. - Explorers Guide (GS-Guide-ADV3-6)
There are potions and chants that can be used on the victims to keep them asleep during their transformations.
Changing into the form of a werewolf can be quite a painful ordeal. Hairs, usually brown, will begin to sprout from every pore of the victims skin. Muscles will bulge and become stronger. The victim's jaw will stretch open painfully as their teeth begin to pop and crack, eventually being replaced by sharp fangs. All sense of reason is lost as the victim gives into animalistic instincts.
The city of Wildwood has been tormented by a werewolf. The Immortal Knight herself has been personally attacked. She now calls upon the Heroes Guild to hunt down this beast and destroy it. You find Earta's son Arnon has been infected. - The Festival of Heroes (GS-ADV1)
Stories abound regarding the Immortal Knight Imbri. Some say that she was bitten and infected by a werewolf during their encounter in Wildwood. If these rumors are true, she met her demise in the Frozen Expanse.
“I-I’m sorry,” she says. “I thought I was strong enough to resist the effects of the curse.” Mournfully, she removes her helm. “I am unworthy to carry the banner of the Immortal Knight. Someone must be found to take my place.” - Imbri - The Frozen Expanse (GS-ADV6)
Following a confrontation with Arnon, you learn that he has been infecting members of the hive. The infected Insectoids crawl on all fours with fang like front pinchers. Their purple skin is covered in black and brown hairs.
Left unchecked, they will overrun Urzon and the rest of the hive. - The Scrying Pool (GS-Epilogue)